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UBC bestows national prize on two heart health researchers
For the first time in its eight-year history, the prestigious Margolese National Heart Disorders Prize is being shared by two recipients – and both are Providence-affiliated researchers.
Drs. Andrew Krahn and Bruce McManus were both singled out by the University of British Columbia Faculty of Medicine for their scientific accomplishments, and for their potential to make further contributions in their fields.
Dr. Krahn, a Principal Investigator at the Centre for Heart Lung Innovation (HLI) and Head of the Division of Cardiology at UBC, received the award for his work on detecting and managing heart rhythm disorders. He is the Paul Brunes Chair in Heart Rhythm Disorders and has established himself as one of the world’s premier authorities on inherited arrhythmia, particularly the most severe, potentially fatal forms. In addition to revealing the specific genetic basis for several congenital arrhythmias, he has helped to refine clinical management of these conditions and has spearheaded efforts to screen for these conditions among high-risk individuals to prevent sudden death.
Dr. Bruce McManus, CEO of the PROOF Centre for Excellence and a Professor of Pathology and Laboratory Medicine at UBC, was recognized for parlaying his insights into inflammatory heart and vascular diseases and transplant vascular disease into the development of diagnostic or predictor biomarkers for heart, lung and kidney failure. An internationally recognized expert in mechanisms of virus-induced myocardial injury, he up-ended conventional wisdom that regarded myocarditis (inflammation of the heart muscle) as a predominantly autoimmune condition. His discoveries, including insights into the ways host cell signaling networks interact with the virus during infection, led to entirely different approaches to diagnosis and therapy for myocarditis.
UBC announced the winners July 26 in tandem with revealing the recipients of the Margolese National Brain Disorders Prize and the Dr. Chew Wei Memorial Prize in Cancer Research. All three prizes include a $50,000 award.